The world of late-night television and music lost a cherished figure on Tuesday morning as Cleto Escobedo III, the band leader of Jimmy Kimmel Live! and leader of Cleto and the Cletones, passed away at the age of 59. The cause of death has not been released, but his absence from the ABC show in recent months due to illness was noted by colleagues and fans alike.
Jimmy Kimmel, Escobedo’s childhood friend and longtime collaborator, paid tribute to him on social media, expressing the profound grief he feels over the loss. Kimmel and Escobedo shared a bond that spanned decades, growing up across the street from each other in Las Vegas. Kimmel recalled, “The fact that we got to work together every day is a dream neither of us could ever have imagined would come true. Cherish your friends and please keep Cleto’s wife, children, and parents in your prayers.”
Escobedo’s musical journey was deeply intertwined with Kimmel’s career. When Kimmel launched his late-night show in 2003, he fought to bring Escobedo on board as the leader of the house band, ensuring that their unique chemistry would be a core part of the show’s energy. “I wanted somebody I had chemistry with. And there’s nobody in my life I have better chemistry with than him,” Kimmel shared. Escobedo’s dynamic presence and musical talent helped shape the tone of Jimmy Kimmel Live! for years, captivating audiences night after night.
Friends and colleagues have also expressed their sorrow and admiration. Jimmy Vega, a longtime friend of Escobedo, reflected, “It is with great sadness that one of my dearest childhood friends Cleto Escobedo III passed away early this morning. I’m crushed and devastated. I’m grateful that I was able to spend some quality time with him, his mom Sylvia, and dad Cleto last Thanksgiving 2024. My love and deepest condolences to his wife Lori and his two children. Also to his mom and dad. God bless your soul, my friend, I’m going to miss you. Prayers for Cleto.”
Escobedo’s influence extended far beyond the television stage. Known for his warmth, humor, and generosity, he was a mentor and inspiration to many musicians. As the leader of Cleto and the Cletones, he helped craft a signature sound that became synonymous with late-night entertainment, blending rhythm, soul, and charisma in every performance.
Jimmy Kimmel himself canceled a recent episode of his show to be by Escobedo’s side, a testament to the deep personal and professional bond they shared. The loss of Escobedo leaves a significant void in both the music and entertainment communities, but his legacy—through his performances, mentorship, and lifelong friendships—will continue to resonate for years to come.
Cleto Escobedo III’s life was defined by music, friendship, and an unwavering passion for his craft. His memory will live on in the melodies he shared, the laughter he inspired, and the countless lives he touched throughout his remarkable career.

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